RWRtoolkit

RWRtoolkit is an open-source scientific software package developed to perform Random Walk with Restart (RWR) analyses on multiplex networks across any species. It provides a set of command-line utilities and R tools designed for biological network modeling at scale.

Features:

• Supports analysis of multiplex networks with species-agnostic architecture.
• Integrates well with omics datasets for downstream biological interpretation.
• Built with R and designed for reproducible, high-throughput inference.

Developers:
Matthew J. Lane, David Kainer, Kyle Sullivan, Mikaela Cashman, John Izaak Miller

DOI: 10.11578/dc.20220607.1
OSTI ID: 1871311
Code ID: 74677
License: GNU General Public License v3.0
Programming Language: R
Research Organization: Oak Ridge National Laboratory (ORNL), Oak Ridge, TN, USA
Sponsoring Agency: U.S. DOE Office of Science, Biological and Environmental Research (BER)
Contract Number: AC05-00OR22725

Repository and additional documentation can be accessed via GitHub - dkainer/RWRtoolkit.